The company offers high-purity, heterobifunctional PEG linkers specifically designed for Antibody-Drug Conjugates (ADCs). Our patented multi-arm heterobifunctional PEG derivatives are aimed at optimizing the drug-to-antibody ratio (DAR) in ADCs by increasing the proportion of drug molecules bound to each antibody, thereby enhancing efficacy. Our products include, but are not limited to, 4ARM-PEG-(NH2)3-COOH, 4ARM-PEG-(MAL)3-NHS, 8ARM-PEG-(NH2)7-COOH, and 8ARM-PEG-(MAL)7-NHS. Additionally, the company provides a variety of high-purity, monodisperse PEG linkers suitable for large-scale commercial ADC production, available in both GMP and non-GMP grades.
Design and synthesis of linkers with multiple functional groups (bifunctional, trifunctional, or multifunctional linkers).
Provision of linkers with specific chemical reactivity (reducible, photosensitive, or enzyme-sensitive linkers).
Development of PEG linkers that combine the excellent properties of PEG with the functionality of linkers, suitable for drug delivery systems and protein labeling.
Supply of PEG linkers with different molecular weights and arm numbers to meet various application needs.
Optimization of linker synthesis processes to improve yield, purity, and production efficiency.
Support for technology transfer, ensuring stable product supply from laboratory scale to industrial-scale production.
