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API Development
home.png Home>API Development>Chemical Synthesis Project for API>Project>Macrocyclic Compounds
Macrocyclic Compounds

We are highly effective in synthesizing macrocyclic compounds, including macrolides, lactams, sulfonamides/sulfonimides, cyclic ethers, and cyclic peptides. We have successfully synthesized over 1,500 macrocyclic compounds, with the largest amount exceeding 30 grams and synthesis steps reaching up to 31.

 

  • A synthesis platform supported by more than 30 experienced chemists.

  • Over 1,500 macrocyclic compounds synthesized.

  • Supported over 10 candidate compounds.

  • Scaled up to 30+ grams with 20 to 31 steps.

  • 15 years of experience in macrocyclic chemistry.

  • 8+ representative cyclization methods.


Representative Cyclization Methods
  • Mitsunobu cyclization

  • RCM (Ring-Closing Metathesis) cyclization

  • Sulfonamide cyclization

  • Lactam cyclization

  • Substitution cyclization

  • Click chemistry cyclization

  • Reductive amination cyclization

  • C-H activation cyclization